[1]江东 郭振宇 麦蕾 冯旭升 郭德荣.围手术期应用度他雄胺对经尿道前列腺等离子切除术出血量的影响[J].中华腔镜泌尿外科杂志(电子版),2014,(05):366-369.[doi:10.3877/cma.j.issn.1674-3253.2014.05.013 ]
　Jiang Dong,Guo Zhenyu,Mai Lei,et al.The effect on bleeding volume of transurethral plasmakinetic prostatectomy by perioperative use of dutasteride[J].,2014,(05):366-369.[doi:10.3877/cma.j.issn.1674-3253.2014.05.013 ]
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围手术期应用度他雄胺对经尿道前列腺等离子切除术出血量的影响()
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中华腔镜泌尿外科杂志(电子版)[ISSN:1006-6977/CN:61-1281/TN]

卷:
期数:
2014年05期
页码:
366-369
栏目:
临床研究
出版日期:
2014-10-31

文章信息/Info

Title:
The effect on bleeding volume of transurethral plasmakinetic prostatectomy by perioperative use of dutasteride
作者:
江东 郭振宇 麦蕾 冯旭升 郭德荣
519000广东珠海，中山大学附属第五医院泌尿外科
Author(s):
Jiang Dong;  Guo Zhenyu;  Mai Lei;  Feng Xusheng;  Guo Derong.
Department of Urology, the Fifth Affiliated Hospital of Sun yat-sen University, Zhuhai 519000, China
关键词:
度他雄胺; 前列腺增生; 切除术; 出血量
DOI:
10.3877/cma.j.issn.1674-3253.2014.05.013
摘要:
目的 探讨术前及术后 1周口服常规剂量度他雄胺对拟行经尿道前列腺等离子切除术的前列腺增生患者术中术后出血量的影响，分析其临床价值。方法 本研究以确诊的 60例前列腺增生患者为处理对象，所有患者随机分成 A、B两组。A组术前及术后均口服度他雄胺 1周，每日 1次，每次0.5mg；B组术前未给予任何抗雄激素药物。患者均经同一手术组医师使用等离子电切镜进行手术。对 A组患者术前使用度他雄胺 1周后前列腺体积、最大血流速度变化及两组患者平均切除每克前列腺的术中出血量、手术时间、术中术后膀胱冲洗液量、镜下血尿时间进行比较。结果 A组患者术前使用度他雄胺 1周前后前列腺体积分别为（ 65.34±8.91）ml、（64.08±9.45）ml，差异无统计学意义（P＞0.05），最大血流速度分别为（ 9.56±1.27）cm/s、（7.59±1.20）cm/s，差异有统计学意义（ P＜0.01）。A组和 B组平均切除每克前列腺的术中出血量分别为（ 0.460±0.054）ml、（0.600±0.065）ml，手术时间分别为（ 86.70±9.07）min、（95.27±10.03）min，术中膀胱冲洗液量分别为（ 33.80±5.20）L、（37.80±5.79）L，术后膀胱冲洗液量分别为（ 22.33±6.16）L、（31.10±6.24）L，镜下血尿时间分别为（ 10.70±2.73）d、（16.43±3.24）d，差异均有统计学意义（ P＜0.05）。结论 围手术期应用度他雄胺可减少 BPH患者术中及术后的出血量，值得临床推广。

参考文献/References:

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备注/Memo

备注/Memo:
基金项目：珠海市科技局课题基金（ PC20041021）
通讯作者：郭德荣，Email：13926927826@139.com
更新日期/Last Update: 2014-10-25