[1]杨波 邓晓俊 温晓飞 陈卫华 刘辉 刘峰 王伟峰 郝继东 万建省 廖国强.经直肠弹性超声穿刺活检联合墨水标记法病理诊断前列腺癌的研究[J].中华腔镜泌尿外科杂志(电子版),2016,10(05):296-300.[doi:10.3877/cma.j.issn.1674-3253.2016.05.002 ]
　Yang Bo,DengXiaojun,WenXiaofei,et al.The clinical research of biopsy of prostate cancer by transrectal ultrasound elastography combined ink marking[J].,2016,10(05):296-300.[doi:10.3877/cma.j.issn.1674-3253.2016.05.002 ]
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经直肠弹性超声穿刺活检联合墨水标记法病理诊断前列腺癌的研究()
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中华腔镜泌尿外科杂志(电子版)[ISSN:1006-6977/CN:61-1281/TN]

卷:
10
期数:
2016年05期
页码:
296-300
栏目:
临床研究
出版日期:
2016-11-05

文章信息/Info

Title:
The clinical research of biopsy of prostate cancer by transrectal ultrasound elastography combined ink marking
作者:
杨波 1 邓晓俊 1 温晓飞 2 陈卫华 2 刘辉 1刘峰 1王伟峰 1郝继东 1万建省 1廖国强 1
201318上海健康医学院附属周浦医院泌尿外科 1；200120上海，同济大学附属东方医院泌尿外科 2
Author(s):
Yang Bo1; DengXiaojun1; WenXiaofei2; ChenWeihua2; LiuHui1; LiuFeng1; WangWeifeng1; Hao Jidong1; WanJiansheng1; LiaoGuoqiang1.
Department of Urology, Zhoupu Hospital Affiliatedto Shanghai University of Medicine&Health Sciences,Shanghai 201318,China;2Department of Urology,East Hospital Affiliatedto Tongji University,Shanghai200120,China
关键词:
前列腺肿瘤; 前列腺穿刺术; 超声; 弹性成像技术; 墨水标记法
DOI:
10.3877/cma.j.issn.1674-3253.2016.05.002
摘要:
目的探讨经直肠超声前列腺穿刺活检联合墨水标记法病理诊断前列腺癌的应用价值。方法 2011年 10月至 2014年 12月，137例患者因血清前列腺特异性抗原（ PSA）升高在上海市周浦医院行前列腺穿刺活检。患者随机分两组，其中普通穿刺组 68例，行常规经直肠超声引导前列腺穿刺活检；弹性超声组 69例，行经直肠弹性超声前列腺穿刺活检联合墨水标记法病理标本，所有标本均按前列腺两侧叶矢状面尖部、中部、底部，前列腺两外侧面中部、底部以及经直肠弹性超声异常处穿刺 1~3针。所有前列腺标本在采集后，在标本末端（外周带）标记上新鲜的黑色墨水后分别分装送病理，比较两组病理结果差异及对诊疗的影响。结果普通穿刺组病理证实为前列腺癌 24例，不典型增生 6例， PIN3例，前列腺增生 35例。弹性超声组病理证实前列腺癌 31例，不典型增生 7例，PIN6例，前列腺增生 25例。弹性超声组前列腺癌检出率显著高于常规超声组（ χ2=3.97，P<0.05）。两组共穿刺 1 543针，其中外周带穿刺阳性者 42例，中央带穿刺阳性者 5例，外周带及中央带均阳性者 8例。 Gleason评分＞7分者 11例，5分≤Gleason评分≤7分者 40例，Gleason评分＜5分者 4例。根据穿刺前列腺所处的位置行内分泌治疗者 9例，前列腺癌根治术 42例，经尿道前列腺电切术 4例。结论经直肠弹性超声前列腺穿刺活检联合墨水标记法有助于提高前列腺癌检出率，协助前列腺癌定位，对疾病的诊断以及手术方法的选择有着较高临床实用价值。

参考文献/References:

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备注/Memo

备注/Memo:
基金项目：浦东新区卫生局卫生科技项目面上项目（ PW2012A-34）；浦东新区卫生系统优秀青年医学人才培养计划（ PWRq2013-17）；浦东新区周浦医院院级课题（ ZP-XM-2012B-22）
通讯作者：廖国强，Email：paulyang228@hotmail.com
更新日期/Last Update: 2016-10-30