[1]郑浩锋,梁观灿,陈延雄,等.经尿道激光与传统电切术治疗非肌层浸润性膀胱肿瘤安全性及疗效的meta分析[J].中华腔镜泌尿外科杂志(电子版),2017,11(02):86-91.[doi:10.3877/cma.j.issn.1674-3253.2017.02.004 ]
　Zheng Haofeng,Liang Guancan,Chen Yanxiong,et al.Laser versus transurethral resection of bladder tumor for non-muscle invasive bladder cancer: a systematic review and meta-analysis[J].,2017,11(02):86-91.[doi:10.3877/cma.j.issn.1674-3253.2017.02.004 ]
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经尿道激光与传统电切术治疗非肌层浸润性膀胱肿瘤安全性及疗效的meta分析()
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中华腔镜泌尿外科杂志(电子版)[ISSN:1006-6977/CN:61-1281/TN]

卷:
11
期数:
2017年02期
页码:
86-91
栏目:
临床研究
出版日期:
2017-04-30

文章信息/Info

Title:
Laser versus transurethral resection of bladder tumor for non-muscle invasive bladder cancer: a systematic review and meta-analysis
作者:
郑浩锋; 梁观灿; 陈延雄; 李腾成; 吴杰英; 司徒杰; 方友强
510630广州，中山大学附属第三医院泌尿外科
Author(s):
Zheng Haofeng;  Liang Guancan;  Chen Yanxiong;  Li Tengcheng;  Wu Jieying;  Situ Jie;  Gao Xin;  Fang Youqiang.
Department of Urology, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China
关键词:
激光; 膀胱肿瘤; 膀胱切除术;  meta分析
DOI:
10.3877/cma.j.issn.1674-3253.2017.02.004
摘要:
目的系统性评价经尿道激光与传统电切术两种手术方式治疗非肌层浸润性膀胱肿瘤的安全性及疗效。方法选用并详细搜索 PubMed、Scopus、Web of science和 Cochrane library的所有比较经尿道激光与传统电切术治疗非肌层浸润性膀胱肿瘤的临床文章，包括随机对照实验、回顾性研究及前瞻性队列研究。结果共 9篇文章，包括 4篇随机对照实验、4篇回顾性研究及 1篇前瞻性队列研究纳入该次分析中。总纳入病例数为 1396例，包括 694例经尿道激光病例及 702例传统电切术病例。从分析中可以发现，虽然经尿道激光在手术时间上与传统电切术无明显差别（WMD=1.63，95% CI=－1.44~4.70，P=0.30），但其平均住院时间（WMD=－1.11，95%CI=－1.71~－0.50，P=0.0004）及术中、术后并发症情况均显著优于传统电切术，且术后 1年（OR=0.87，95%CI=0.59~1.27，P=0.47）及 2年复发率（OR=0.70，95% CI=0.46~1.09，P=0.11）无明显区别。结论经尿道激光治疗非肌层浸润性膀胱肿瘤术式较传统电切术安全，且效能不低于传统电切术，应作为微创治疗非肌层浸润性膀胱肿瘤的重要方案之一。

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备注/Memo

备注/Memo:
基金项目：广东省科技计划项目（2013B021800084）；高校基本业务费，青年教师培育项目（14ykpy25）
通讯作者：方友强，Email：Fang1573@hotmail.com 注：郑浩锋和梁观灿为共同第一作者
更新日期/Last Update: 2017-04-20