[1]袁润强,郑少斌,敖道畅.CIK 细胞回输联合沙培林膀胱灌注预防表浅膀胱癌术后复发[J].中华腔镜泌尿外科杂志(电子版),2009,(03):214-217.
 YUAN Run-qiang,ZHENG Shao-bin,AO Dao-chang.Cytokine induced killer(CIK) cells infusion combination with intravesical instillation of OK-432 in the prophylaxis of local recurrence after resection of bladder cancer[J].,2009,(03):214-217.
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CIK 细胞回输联合沙培林膀胱灌注预防表浅膀胱癌术后复发()
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中华腔镜泌尿外科杂志(电子版)[ISSN:1006-6977/CN:61-1281/TN]

卷:
期数:
2009年03期
页码:
214-217
栏目:
出版日期:
1900-01-01

文章信息/Info

Title:
Cytokine induced killer(CIK) cells infusion combination with intravesical instillation of OK-432 in the prophylaxis of local recurrence after resection of bladder cancer
作者:
袁润强郑少斌敖道畅
广东省中山市人民医院泌尿外科,528403,南方医科大学附属南方医院泌尿外科,广州,510000
Author(s):
YUAN Run-qiangZHENG Shao-binAO Dao-chang
关键词:
膀胱肿瘤复发沙培林CIK细胞
摘要:
目的 探讨CIK 细胞回输联合沙培林膀胱灌注预防表浅膀胱癌术后复发的疗效.方法 对67例多发性浅表性膀胱癌患者术后进行免疫治疗,其中CIK 细胞回输联合沙培林膀胱灌注36例,单用沙培林膀胱灌注31例.随访12~26 个月,监测两组患者治疗后是否复发以及复发的时间.结果 联合治疗组无肿瘤复发率97.22%(35/36),肿瘤复发率2.78%(1/36),复发1例为PT1G2-3 ,复发时间为术后第24 个月.单用沙培林组无肿瘤复发率80.65%(25/31),肿瘤复发率19.35%(6/31),两组病例在肿瘤复发率的比较差异有统计学意义(P< 0.05).结论 CIK 细胞回输联合沙培林膀胱灌注可有效预防浅表性膀胱癌术后复发,远期效果有待进一步观察.

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备注/Memo

备注/Memo:
中山市卫生局研究基金(B200564)
更新日期/Last Update: 1900-01-01