[1]陈富昌 李继清 刘刚 万良 蓝志相 吴明文 罗权海.微通道与标准通道经皮肾镜取石术治疗肾结石的系统评价[J].中华腔镜泌尿外科杂志(电子版),2014,(05):344-349.[doi:10.3877/cma.j.issn.1674-3253.2014.05.008 ]
　Chen Fuchang*,Li Jiqing,Liu Gang,et al.Efficacy and safety of minimally invasive percutaneous nephrolithotomy and standard percutaneous nephrolithotomy in treatment of renal calculi: a systematic review[J].,2014,(05):344-349.[doi:10.3877/cma.j.issn.1674-3253.2014.05.008 ]
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微通道与标准通道经皮肾镜取石术治疗肾结石的系统评价()
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中华腔镜泌尿外科杂志(电子版)[ISSN:1006-6977/CN:61-1281/TN]

卷:
期数:
2014年05期
页码:
344-349
栏目:
临床研究
出版日期:
2014-10-31

文章信息/Info

Title:
Efficacy and safety of minimally invasive percutaneous nephrolithotomy and standard percutaneous nephrolithotomy in treatment of renal calculi: a systematic review
作者:
陈富昌 李继清 刘刚 万良 蓝志相 吴明文 罗权海
535000钦州，广西钦州市第一人民医院（陈富昌、万良、吴明文）； 530021南宁，广西壮族自治区人民医院泌尿外科（李继清、刘刚、蓝志相）； 530021南宁，广西壮族自治区人民医院研究生（陈富昌、罗权海）
Author(s):
Chen Fuchang*;  Li Jiqing;  Liu Gang;  Lan Zhixiang; Luo Quanhai.
Department of Urology,the First People's Hospital of Qinzhou,Guangxi 535000,China
关键词:
经皮肾镜; 肾结石; 微通道; 标准通道; 系统评价
DOI:
10.3877/cma.j.issn.1674-3253.2014.05.008
摘要:
目的系统评价微通道经皮肾镜取石术（ MPCNL）与标准通道经皮肾镜取石术（ SPCNL）治疗肾结石的临床疗效与安全性。方法计算机检索 PubMed、CochraneLiabrary、EMbase、CNKI、维普数据库，检索时限从 2001年 1月 1日至 2013年 2月 1日。筛选两种通道经皮肾镜取石术（ PCNL）治疗肾结石的随机对照试验（ RCT）及非随机对照试验（ non-RCT）并进行文献质量评价，采用 RevMan5.1软件进行统计学处理。结果共纳入 6个 RCT及 2个 non-RCT研究，1163例患者。结果显示：两种通道处理鹿角型结石的清除率无显著差别[OR=0.93，95%CI(0.54，1.59)，P=0.79]；MPCNL处理肾盏多发性结石的清除率高于 SPCNL[OR=2.01，95%CI (1.19，3.38)，P=0.009]，但其处理单纯肾盂结石的清除率低于 SPCNL[OR=0.45，95%CI(0.25，0.79)，P=0.006]。在手术时间方面， SPCNL处理 3种类型结石均优于 MPCNL，分别为 [MD=22.7、9.77、13.04，95%CI (17.73，27.72)、(7.12，12.42)、(10.23，15.85)，P＜0.01、＜0.01、＜0.01]。在发热方面，两种通道手术无明显差别[OR=0.92，95%CI(0.61，1.38)，P=0.68]，但在手术明显出血的发生率方面，MPCNL低于SPCNL[OR=0.32，95%CI(0.16，0.61)，P=0.0007]。结论 MPCNL与 SPCNL在处理不同类型结石各自有优点，MPCNL适合处理肾盏多发结石及较小的肾盂结石， SPCNL适用于治疗单纯较大的肾盂结石。

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备注/Memo

备注/Memo:
基金项目：广西卫生厅重点科研课题（桂重 200722）
通讯作者：刘刚，Email：dr.lg@163.com
更新日期/Last Update: 2014-10-25